Anticipating smallpox as a bioterrorist weapon
نویسندگان
چکیده
منابع مشابه
Anticipating smallpox as a bioterrorist weapon.
The treat of bioterrorism means it is important to be able to diagnose smallpox. The responsibility for the initial recognition of cases lies with clinicians, and early diagnosis is the key to the successful control of an outbreak. Unless rapidly contained, a bioterrorist release of smallpox would constitute not just a national but a global threat to health. This brief review sets smallpox in i...
متن کاملModeling potential responses to smallpox as a bioterrorist weapon.
We constructed a mathematical model to describe the spread of smallpox after a deliberate release of the virus. Assuming 100 persons initially infected and 3 persons infected per infectious person, quarantine alone could stop disease transmission but would require a minimum daily removal rate of 50% of those with overt symptoms. Vaccination would stop the outbreak within 365 days after release ...
متن کاملModeling Potential Responses to Smallpox as a Bioterrorist Weapon Appendix I: A Mathematical Review of the Transmission of Smallpox
The mathematical model we described requires the researcher to preset the average number of disease-susceptible persons infected by an infectious patient (i.e., the rate of transmission). To obtain historical data describing the average number of persons infected per infectious person, we examined the literature for data regarding the rate of transmission. Since there are already a number of ex...
متن کاملResponding to Bioterrorist Smallpox in San Antonio
We used discrete-event simulation to help the San Antonio public health and acute medical care communities to plan their response to a bioterrorist attack. The analysis, based on a scenario positing an attack with aerosolized smallpox, indicated the resources and strategies needed for an effective response. We found that a mixture of public-health measures designed to stop the spread of the dis...
متن کاملCountermeasures to the bioterrorist threat of smallpox.
Variola, the agent of smallpox, is a bioterrorist threat, as is monkeypox virus, which also occurs naturally in Africa. Development of countermeasures, in the form of improved vaccines, antiviral drugs, and other therapeutic strategies are a high priority. Recent advances in molecular biology and in animal model development have provided fresh insight into the virulence determinants for smallpo...
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ژورنال
عنوان ژورنال: Clinical Medicine
سال: 2003
ISSN: 1470-2118,1473-4893
DOI: 10.7861/clinmedicine.3-3-255